![]() ![]() However, unlike in manifest glaucoma with typical VF defect, assessing glaucoma risk in early suspected cases is clinically challenging. Therefore, early suspicion of structural damage and prediction of ongoing glaucomatous damage provide opportunities to prevent serious visual impairment 5, 6, 7. In most cases, structural changes in the optic disc rim and peripapillary retinal nerve fiber layer (RNFL) precede functional changes in the VF 2, 3, 4. Glaucoma is characterized by progressive optic nerve damage that causes progressive visual field (VF) defect, which eventually lead to blindness if left untreated 1. Careful examination of the optic nerve head and vascular structures can help to predict the risk of glaucoma conversion in eyes with large optic disc cupping. An HR-matched scoring system based on initial fundus photography predicted glaucoma conversion with specificity of 90.4%. From a median follow-up of 11.3 years, 26.6% of eyes (n = 144) developed RNFLD within a median of 5.1 years. Characteristics for optic disc configuration (including CDR, vertical cupping, ISNT rule, disc ovality, peripapillary atrophy -to-disc area ratio, and lamina cribrosa pore visibility) and blood vessels (including central retinal vessel trunk nasalization, bayoneting of vessels, baring of circumlinear vessels, history of disc hemorrhage and vessel narrowing/sclerotic change) were evaluated. Five hundred forty-two eyes of 271 subjects who had a vertical cup-to-disc ratio (CDR) ≥ 0.6 without RNFLD were enrolled. This study aimed to investigate the risk factors for glaucoma conversion and progression in eyes with large optic disc cupping without retinal nerve fiber layer defect (RNFLD). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |